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Hyperinsulinaemia in cancer
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Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1) Diabetes Care
They need to take insulin shots because their bodies can't make any of their own insulin
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Increased insulin secretion can also occur via G q /phospholipase C (PLC) signalling, where inositol trisphosphate 3 (IP 3 ) binds to its receptor (IP 3 R) and diacylglycerol (DAG) binds to the ryanodine receptor to stimulate calcium-induced calcium release [17]
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Childhood obesity affects multiple organs in the body and is associated with both marked morbidity and ultimately premature mortality