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Examining 168 pregnant women exposed to a GLP1-RA during the first trimester of pregnancy, alongside two reference groups (comprising pregnant women diagnosed with diabetes mellitus and overweight/obese pregnant women), we did not identify a specific pattern of birth defects

However, here are some general guidelines on who may qualify for GLP-1 medications: Type 2 Diabetes Diagnosis GLP-1 medications are primarily indicated for the treatment of type 2 diabetes

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Especially with people who quit standard doses because of side effects, often tolerate microdose semaglutide just fine

Other clinically relevant GI complications include cholelithiasis, which occurred about 50 % more often, and gastroesophageal reflux disease (GERD), which occurred roughly twice as often, in patients receiving GLP-1 therapies compared with placebo [33]