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Obesity medicine physician Jessica Duncan discusses the article "GLP-1 weight regain: Why stopping medication leads to weight return." Jessica explains that expecting to maintain weight loss after abruptly stopping GLP-1 therapy is unrealistic because it ignores the physiological forces that defend a person's prior weight

In animal models, GLP-1 agonists have been shown to significantly delay the onset and severity of experimental autoimmune encephalopathy symptoms, as well as to increase nerve myelination and brain weight