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The FDA has made clear that compounded GLP-1 products are not evaluated for safety, efficacy, or quality

One issue that comes up is embarrassment

Originally approved for type 2 diabetes management, Ozempic has gained significant attention for its remarkable effectiveness in weight loss

Interestingly, subsequent studies showed that GLP-1R mRNA was reduced in samples obtained from inflamed area of the colon in IBD patients (Bang-Berthelsen et al

Other considerations include if this class of medications is dropped from coverage, patients on the drugs will need to find other ways to pay for it if they want to continue, the affordability and availability of the medications, and what will the long-term impact be if patients stop taking the medications suddenly

While losing weight on these meds is amazing and can truly be life changing, the weight you lose is total body weight reduction, not just fat reduction