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Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles
The FFA-induced rise in intracellular Ca 2+ is substantially reduced when cells are cultured in a Ca 2+ free medium, and is abolished upon treatment of cells with the Ca 2+ channel inhibitor nicardipine [292] or when using BSA (which binds fatty acids) [251]

19 The Effect of GLP-1RAs on Blood Pressure A meta-analysis of 16 RCTs showed that use of GLP-1RAs leads to a moderate BP reduction in patients with hypertension
Depression According to current theories of the biology of depression [334

Chen S, Saeed A, Liu Q, Jiang Q, Xu H, Xiao GG, et al
