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The transaction has an obvious economic logic: if the patent is genuinely likely to be upheld (and the generics entry blocked), both parties are no better off litigating

Weight-related quality of life, health utility, psychological well-being, and satisfaction with exenatide once weekly compared with sitagliptin or pioglitazone after 26 weeks of treatment

Outcomes were presented as mean differences (MD) or risk ratios with 95% confidence intervals

A systematic review and meta-analysis analysing tirzepatides gastrointestinal effects found that the incidence of side effects was dose-dependent, with 39% of patients on 5mg experiencing GI adverse events, 46% on 10mg, and 49% on 15mg

Potential for Non-Alcoholic Fatty Liver Disease (NAFLD) Improvement: Preliminary studies suggest that tirzepatide may have beneficial effects on non-alcoholic fatty liver disease (NAFLD), a common condition associated with obesity and insulin resistance

Body weight affects the peak concentration and overall exposure, but not the half-life itself