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In this review we consolidate literature regarding preclinical and clinical data related to the interaction between GLP-1RA use and risk for PDAC

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The discovery of GLP-1 drugs represented a genuine breakthrough in addressing one of the worlds most common health afflictions, and the immediate rush to access them signaled just how valuable they are to patients

It then develops into a weight disorder called obesity, defined as a BMI 30 kg/m 2 (2)

New agents being considered for the treatment of obesity are analogs of the peripheral peptide hormones, like glucagon-like peptide-1 (GLP-1), peptide YY, and glucagon, and some are antagonists for receptors, like the ghrelin receptor
