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Research indicates that the body's homeostatic mechanisms actively defend against sustained weight loss through increased hunger signaling and reduced satiety hormone production

S., Pharmacotherapy of Obesity: An Update on the Available Medications and Drugs Under Investigation, EClinicalMedicine 58 (2023): 101882, 10.1016/j.eclinm.2023.101882

Supplements arent regulated like prescription medications

Figure 5 Double-labeling fluorescence IHC of pancreata from healthy humans and those with diabetes showed complete co-localization of the GLP-1R and insulin in all islets and islet-like samples (73)

Atypical anorexia nervosa Patients with atypical anorexia nervosa, a subtype of other specified feeding and eating disorder (OSFED), meet all criteria for anorexia nervosa except that, despite significant weight loss, their weight remains within or above the normal range (American Psychiatric Association, 2013)

Compare weekly averages rather than single readings to spot meaningful trends