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The development of dual GIPRGLP1R coagonists that bind to either one or the other receptor (sequence-mixed dual agonists) has emerged as an innovative therapeutic strategy for obesity and type 2 diabetes

Several randomized controlled trials have demonstrated the benefits of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on ischemic stroke in patients with diabetes

however, they have important limitations in achieving sustainable long-term weight loss

Doctors warn against the move

GLP-1 drugs such as Ozempic are accelerating interest in protein to address the loss of lean muscle mass that can accompany rapid weight loss.

During intubation, endoscopy, and recovery, there were no instances of retained gastric solids, pulmonary aspiration, gastroesophageal regurgitation, or hypoxia