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However, some patients find the pill causes slightly milder nausea because the dose absorbs more gradually

Key Takeaways: Rybelsus and Jardiance, originally designed for diabetes management, have shown potential for weight loss in individuals with type 2 diabetes

Causes / Risk Factors: Aging (most common) Obesity Joint overuse or trauma Genetics Pathophysiology: Cartilage wears down bones rub together osteophytes form joint space narrowing Clinical Features: Joint pain worsens with activity, relieved by rest Morning stiffness 1 hour Symmetrical involvement Common joints: small joints of hands (MCP, PIP), wrists, feet Systemic features: fatigue, low-grade fever, rheumatoid nodules Deformities in chronic cases: ulnar deviation, swan neck, boutonniere Investigations: Labs: positive rheumatoid factor (RF), anti-CCP antibodies, elevated ESR/CRP X-ray: joint erosions, osteopenia Management: Disease-modifying antirheumatic drugs (DMARDs): methotrexate, hydroxychloroquine NSAIDs for symptom relief Corticosteroids for flares Physiotherapy To view or add a comment, sign in It took 26 years to publish this study (just a couple of years shy of half of my life)

Your doctor can recommend effective treatment options

Personalizing Your Semaglutide Plan With PlexusDx Genetic Testing Individual responses to semaglutide vary based on genetic factors affecting how your body processes GLP-1 receptor signals

White fat cells store triglycerides and release fatty acids when energy is needed