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(3) Lack of Early Indicators- prior to the cardiovascular outcomes trials (CVOTs), there was no strong evidence or clear biological indicators suggesting that this class of drug would have a direct effect on cardiovascular health

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The GLP-1 receptor agonist exenatide reduces serum TSH by its effect on body weight in people with type 2 diabetes

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[DOI] [PubMed] [Google Scholar] 20.Stark J.E., Cole J.L., Ghazarian R.N., Klass M.J