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Description
Conclusion In conclusion, the preclinical and clinical studies demonstrated that GLP-1RAs and SGLT-2is act directly or indirectly on their receptors by crossing the BBB

For treatments like Mounjaro or Wegovy, a maintenance dose is often possible, but it requires careful monitoring to ensure it remains effective and safe for you

PMID: 40029954 Chen J, Xu Y, Cao P (2025) The role of the gut-brain axis in diseases

SGLT2 inhibitors (sodium-glucose co-transporter-2 inhibitors) such as empagliflozin, dapagliflozin, or canagliflozin offer cardiovascular, renal and heart failure benefits without the gastrointestinal side effects associated with GLP-1 agonists

Those needing to change their weekly injection day may ensure at least 48 hours between doses

Doses dropped
