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14 However, in two studies that included participants not enrolled in the SURPASS and SURMOUNT studies, ie, a large number of individuals who switched from other GLP-1 RAs to tirzepatide, those who transitioned from semaglutide experienced greater weight loss with tirzepatide treatment

But there was a problem: the human body breaks down GLP-1 very fast, lasting only minutes in the bloodstream

Toxicon 59 , 464471 (2012)

Polonsky, PhD, CDCES & Susan Guzman, PhD (Behavioral Diabetes Institute) that reveals psychosocial forces behind diabetes self-management tools to break through resistance and inspire change

For monitoring of individuals taking GLP-1s, DXA could be considered yearly or every two years, yet such a timeline may impede the identification of early muscle loss and the institution of appropriate interventions