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GLP-1RAs for the prevention of osteoporosis and fracture are controversial

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Patients with DT2 without obesity or excess weight with comorbidities can use liraglutide 1.8mg (daily, subcutaneous) and semaglutide 1mg (weekly, subcutaneous), or 14mg (daily, oral) for glycemic control

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However, the added agonism of GIPR seems to have a more positive impact on weight loss
doi:10.1001/jamacardio.2021.5613 Vaduganathan M, Mensah GA, Turco JV, Fuster V, Roth GA