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[1] Response to treatment is assessed differently depending on the medicine: Orlistat : if a patient has not lost at least 5% of their initial body weight after 12 weeks of treatment, orlistat should generally be discontinued

Genetic predispositions in GLP1R, GIPR, and metabolic genes may provide context for expected response patterns but do not determine exact medication response

Between-study heterogeneity was moderate (Q = 13.12, p = 0.157

The reduction of neuronal damage in this model is further demonstrated by the modulation of ATF-3 expression

Trend 2010-2018 in the Clinical Use of GLP-1 Receptor Agonists for the Treatment of Type 2 Diabetes in Routine Clinical Practice: An Observational Study From Northeast Italy

However, the cost of treatment can be a significant hurdle