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The Pharmacovigilance Risk Assessment Committee (PRAC) of the European Medicines Agency (EMA) is reviewing data on the risk of suicidal thoughts and thoughts of self-harm with glucagon-like peptide-1 agonist (GLP-1a), including Ozempic (semaglutide), Saxenda (liraglutide) and Wegovy (semaglutide)

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Initially designed for managing type 2 diabetes, these GLP-1 receptor agonists have proven so effective at curbing appetite that theyre now being prescribed off-label for weight loss