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This combination approach is generally not recommended for pregnant women, people with type 1 diabetes, those with a history of eating disorders, or patients with certain kidney or liver disorders

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Start with a medical evaluation to see whether GLP-1 microdosing is right for you

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For both Zepbound and Retatrutide, there are concerns about: Pancreatitis (inflammation of the pancreas) Gallbladder problems Thyroid tumors (Zepbound includes a warning about medullary thyroid carcinoma based on animal studies) Low blood sugar, especially if combined with other diabetes medications People with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 should not take these drugs