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About side effects and management: "What are the most common side effects during the first few weeks?" "How should I adjust my diet to minimize gastrointestinal side effects ?" "When should I call your office about side effects versus managing them at home?" "Are there any supplements I should take alongside this medication ?" "Could this medication interact with anything I currently take ?" Side effect questions show maturity and realism

Results of this study suggest that liberalizing the withholding guidelines for GLP-1 RAs preoperatively should be considered

Lifestyle modification remains the fundamental basis of MASLD treatment, and pharmacological treatment is increasingly recognized as fundamental support, mainly in patients with biopsy-confirmed MASH, significant fibrosis ( F2), or cardiometabolic comorbidity 8

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The initial 3 mg dose is primarily for tolerability and not expected to provide full glycaemic control

The preliminary data from observational studies like the NYU cohort and the Jorge outcomes study provide the justification for these trials, which will produce the higher-quality evidence needed for guideline recommendations