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In conclusion, combination of metformin and liraglutide has synergistic protective effects on endothelial function

Stopping GLP-1 receptor agonists 14 days prior to total hip or knee arthroplasty may reduce several key risk factors associated with anesthesia complications, according to results presented here.“Specifically for semaglutide, stopping that medication 14 days before surgery is safest based upon the dataset that we have to minimize your risks with anesthesia, especially when

FDA Enforcement Actions and Safety Concerns In September 2025, the FDA issued over 50 warning letters to compounders marketing GLP-1 products as generic equivalents to FDA-approved drugs

And West Virginians used them at the highest rate

While the nutritional needs of GLP-1 users are not drastically different from the general population, according to a dietician, the key distinction lies in reduced food intake

By Patricia Van