dpp 4 inhibitors and glp 1 agonists together Role of DPP-4 in Clinical Practice Renoprotective Effects of DPP-4 Inhibitors

Chapman MB, Norwood DA, Price C, et al

As a result, GLP-1RAs show great promise as obesity treatments [114]

[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Wang N., Zhou Y., Erasto Ngowi E., Qiao A

Is there a risk to (or for) pregnancies

In the central nervous system, the action of GLP-1 and GLP-1RAs on its receptors can affect a variety of brain functions including satiety, thermogenesis, influence blood pressure, neurogenesis, neurodegeneration, retinal repair, and change energy homeostasis [16-20]

Given existing evidence, triple combination therapy can be expected to provide additional cardiorenal protection, although further randomized controlled trials are needed to determine whether triple combination therapy actually has additive or synergetic effects compared with mono or dual therapy