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Gradual dose reduction over 4-8 weeks allows the body to readjust, and thyroid levels should be checked both during and after the taper, since weight stabilization changes levothyroxine requirements once again

(2022) 9:1019120/BIBTEX

In addition to the well-known effects of GLP-1 and GLP-1 RA in improving insulin sensitivity and reducing body weight, at central levels, GLP-1 and GLP-1 RA might exert regulating effects on GhRH release, and on concomitant gonadotropin secretion, likely by activating the kisspeptin hypothalamic system, a key regulator of the pulsatile release of GnRH from GnRH neurons

With medical supervision both can be appropriate complementary additions without supervision the combined effect requires monitoring

Personas con sobrepeso u obesidad con riesgos de salud relacionados con el peso