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294,295 In inflammation regulation, NF-B is a key transcription factor

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H 2 O 2 -induced autophagic responses were attenuated when ERK1/2 activity were suppressed by their inhibitor U0126, suggesting that ERK activation are required for autophagy induced by H 2 O 2 in HUVECs, implying that an ERK1/2-HDAC6 pathway is at least partially involved in H 2 O 2 -mediated autophagy

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What began as a niche class of diabetes medications has evolved into one of the most transformative therapeutic categories in modern medicine, with GLP-1 receptor agonists now reshaping obesity treatment, metabolic care and potentially even neurodegenerative disease management