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The side effect profile of DPP-4 inhibitors is favorable, there are few treatment-limiting adverse effects and DPP-4 inhibitors have shown cardiovascular safety

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To minimise gastrointestinal side effects that may contribute to dehydration, take Rybelsus exactly as prescribed: on an empty stomach with no more than 120 ml of water, at least 30 minutes before eating, drinking, or taking other oral medications

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