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The results concluded that TNF- and IL-6 serum levels were significantly higher in manic, depressive and mixed-state patients compared with controls, but IL-18 was significantly higher only in depressive states

However, many peptides work locally, never reach the blood stream, and would never be called hormones

doi: 10.1038/nature22394 [DOI] [PMC free article] [PubMed] [Google Scholar] 22

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Injectionsite reactions: Redness, swelling, or irritation (generally mild and transient) [11]
