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Procedures such as sleeve gastrectomy and Roux-en-Y gastric bypass produce average weight reductions of 25 to 35% and remain the most durable interventions available for severe obesity and obesity-related metabolic disease

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This is why the studies for CVD, chronic kidney disease (CKD), and obstructive sleep apnea (OSA) were so significant

[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Ren H, Cook JR, Kon N, Accili D