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However, because glucagon-like peptide-1 receptor agonists work to slow gastric emptying, a safety concern has been raised in patients undergoing deep sedation or general anesthesia regarding gastric aspiration, and considering their long half-life in the blood, they are difficult to manage in the perioperative period

Out-of-Pocket Costs Drive Abandonment Especially in Obesity While payer restrictions and coverage gaps contribute to GLP-1 therapy abandonment, out-of-pocket (OOP) costs remain the most consistent and powerful predictor of non-adherence