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And the procedure is not reversible. He says the following complications can occur in about 20 percent of cases: Infection Bleeding Gastrointestinal leaks Gastric reflux Narrowing of the gastric sleeve Leakage in the stomach or small intestine Diarrhea Blood clots Still, Marina Kurian, MD, a clinical associate professor in the department of surgery at NYU Grossman School of Medicine in Manhattan, highlights the overall safety of weight loss procedures

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Heffron and his colleagues also conducted a subgroup analysis, collecting trials that compared GLP-1 agonists with DPP-4 inhibitors (an older class of diabetes medications), both of which raise blood levels of GLP-1