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2813-LB: CT-388, a cAMP Signal-Biased GLP-1/GIP Receptor Agonist, Achieves Clinically Meaningful Weight Loss in People With Overweight/Obesity: A 48-Week Phase 2 Study LINGVAY I, JASTREBOFF A , LENDER D, BAYS H, CHAKRAVARTHY M, LE ROUX C, SHEARER-KANG E, PALERMO G, WILLIS J, STEINBERG A, SHARP S, BOLLEPALLI S, KIM K

In the isolated perfused rat pancreas, co-infusion of GLP-1 with a specific somatostatin receptor 2 (SSTR2) antagonist (PRL-2903) abolishes the GLP-1-induced suppression of glucagon secretion [582]

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