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Material and methods Study design and dataset description This multicentre, prospective, observational cohort study was conducted involving six participating centres that are members of the European Network of Teratology Information Services (ENTIS) in five countries: Germany, Israel, Italy, Switzerland, and the UK

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Distinct semen microbiome clusters dominated by Lactobacillus , Prevotella , or Streptococcus have been identified, with the Lactobacillus -dominant cluster associated with the best semen quality and fertility outcomes