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Nausea is the most challenging side effect for many people but is usually dose-related and temporary

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Genetic differences in peptide sensitivity also play a role

Diabetes 52:17861791 Hare KJ, Vilsbll T, Asmar M, Deacon CF, Knop FK, Holst JJ (2010) The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

But one of the most important questions people ask is whether exercise is necessary while taking semaglutide, and what type of exercise works best

Although this was usually accompanied by weight loss, P4 was the only participant to gain weight (7 kg) during the study