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Int J Pharm 611:121312121312 Pocai A, Carrington PE, Adams JR, Wright M, Eiermann G et al (2009) Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice

The trial demonstrated a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal heart attack, or nonfatal stroke (hazard ratio 0.80, 95% CI 0.72-0.90)

Because human clinical trials are extremely limited, the therapeutic value, risks, interactions, and long-term effects of BPC-157 remain uncertain

Victoza reduces hemoglobin A1c by about 1.5% and reduces all-cause mortality

However, the wide variation in reported muscle loss percentages across different studies and conditions strongly suggests that the amount of muscle lost is not a fixed, unavoidable consequence

Egharevba GO, Dosumu OO, Oguntoye SO, Njinga NS, Dahunsi SO, Hamid AA, Anand A, Amtul Z, Priyanka U