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The Link Between GLP-1 Drugs and Severe Stomach Problems The very mechanism that makes these drugs effective for weight lossslowing digestionis also what may be at the heart of these severe injuries

The GLP-1 receptor undergoes a shape change during binding which leads to different biological responses

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Cases were also identified in which doctors prescribed the drugs for their own use without creating medical records

Primarily, they act on the hypothalamus to enhance satiety, delay gastric emptying, and reduce caloric intake, leading to a preferential reduction in fat body mass (FBM)