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In nutrient-replete states, GLP-1induced insulin signaling suppresses adipose lipolysis, whereas during reduced caloric intake and relative glucose scarcity, lipid substrates become the dominant oxidative fuel [59, 60]

Clinically, these reductions in physiological drive may provide a window of opportunity in which behavioral strategies such as stimulus control, self-monitoring, and structured eating routines may be adopted more consistently

Yin H, Wang W, Yu W, et al

Meal timing matters as much as food quality

Six studies used a composite outcome, and the component outcomes differed

To address these gaps, researchers conducted a randomized, controlled, crossover, single-blind, free-living intervention trial in both apparently healthy adults and adults at moderate risk for developing CVD 1