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These trials will provide definitive efficacy and safety data needed for regulatory submissions, with results expected in the coming years

AWARD-7 enrolled adult patients with T2D (A1c, 7.5%10.5%) and CKD stages 34 who were being treated with ACEi or ARBs and found that dulaglutide (0.75 or 1.5 mg subcutaneous once weekly) achieved similar glycemic control to insulin glargine but had significantly less eGFR decline (mean 0.7 vs 3.3 mL/min/1.73 m 2 , respectively

Some people report fatigue as a side effect when starting these injections, especially during the initial adjustment period

Talk to Your Doctor: Only a healthcare practitioner can evaluate whether these medications are suitable for you or not

You also get access to personalized genetic insights through the optional Precision Peptide Genetic Test ($99 after month one), allowing your provider to tailor dosing and side effect strategies to your unique biology

Research suggests Akkermansia may influence GLP-1 secretion through improvements in gut barrier function and reduction of inflammation rather than directly stimulating GLP-1 production