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As gastrointestinal cancer outcomes were secondary or exploratory endpoints in the majority of included trials, these analyses are inherently vulnerable to type I error, outcome misclassification, and inadequate statistical power
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Recent findings demonstrated that in overweight or obese adults, GLP-1 receptor agonists and phenterminetopiramate are the best drugs to reduce body weight
Semaglutide versus liraglutide Liraglutide was the first long-acting GLP-1 agonist to achieve widespread use
