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doi: 10.1001/jamapsychiatry.2023.5371, 63

Sleep Apnea J 12(1):2334 [Google Scholar] 33.Kow CS, Hasan SS, Naing L, Merchant HA (2025) Effects of GLP-1 receptor agonists on obstructive sleep apnea severity: a systematic review and meta-analysis of clinical trials

3.2 Clinical application of GLP-1RAs GLP-1RA has been widely acknowledged at home and abroad for its hypoglycemic effects, safe use and beneficial effect on human metabolism
Liraglutide, the glucagon-like peptide-1 receptor agonist, has anabolic bone effects in diabetic Goto-Kakizaki rats
Furthermore, the hazard ratio for medullary thyroid cancer was 1.78 (95% confidence interval 1.04 to 3.05) and the reporting ratio in a complementary pharmacovigilance analysis based on the World Health Organizations database VigiBase was 30.5 (95% confidence interval 25.1 to 37.2) compared with other diabetes drugs.7 These data prompted the European Medicines Agency to raise a safety concern and start an investigation,8 which concluded that the available evidence does not support a causal association.9 We conducted a cohort study using nationwide data from three Scandinavian countries to investigate whether GLP1 receptor agonist use is associated with increased risk of thyroid cancer

And several studies suggest that exenatide increased expression levels of BDNF in AD mice hippocampus and cortex (141, 203, 204)
