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While we are not aware of any study to date that has directly investigated the effects of GLP-1RAs on astroglial glycogen storage and/or turnover, studies in human and rodent skeletal muscle and hepatocytes indicate that GLP-1 receptor signalling enhances glycogen synthesis [229,230]

Furthermore, no undesirable or safety issues have been identified so far as a result of offtarget impacts of DPP4is on other endogenous substrates

This can lead to deficiencies in essential vitamins and minerals, which can affect almost every system in the body, leading to weakness, fatigue, and decreased immune function

Cognitive effects : Topiramate is well known for causing cognitive side effects, including difficulty with concentration, memory problems, and slowed thinking (sometimes referred to colloquially as "Dopamax")

503A pharmacies on a patient-specific prescription basis