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Treatment usually starts at 0.25 mg once weekly for 4 weeks, then increases to 0.5 mg

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However, studies have uncovered many other potential benefits, such as treating obesity, reducing the risk of heart disease, and possibly managing polycystic ovary syndrome (PCOS)

The safety profile of retatrutide looks similar to other drugs in this class, with some important caveats

Melanie Cree, director of the University of Colorados PCOS multidisciplinary clinic and pediatric endocrinologist at Childrens Hospital Colorado, is the main investigator on a clinical trial testing semaglutide in 80 obese girls and women with PCOS aged 12 to 35