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mibavademab, a leptin receptor agonist (NCT06373146)

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Furthermore, a VMH knockout mouse showed lower energy expenditure and UCP1 expression in BAT62,63)

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An important consideration when analyzing meal-induced GLP-1 secretion is whether GLP-1 was measured in systemic or portal vein blood, whether the samples were taken in relation to oral meals or rather to intragastric infusion of liquid (or semiliquid) meals, and whether total or active GLP-1 was measured

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