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Approval is expected in late 2026 to early 2027, with Canadian availability following

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Based on HE and Oil red O staining results, we uncovered that the HFD mice exhibited improved lipid accumulation and hepatocyte swelling and necrosis after TZP treatment, which was confirmed by Oil red positive area and NAFLD Activity Score (Figure 3A and 3B)

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However, trends showed a dose-dependent increase in gastrointestinal disorder risk (RR ranging from 1.52 to 2.70) and greater cardiovascular protection at higher doses (RR = 0.76)