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The glucose-dependent insulin secretion of GLP-1 drugs provides a natural safety buffer

reported a three-fold higher risk of major depression, and a doubled risk for anxiety and suicidal behavior in a large ( n = 11,683,623) retrospective study of GLP-1RA users utilizing the TrinetX database (100)

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The Effects of GLP-1 Receptor Agonists on Visceral Fat and Liver Ectopic Fat in an Adult Population With or Without Diabetes and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Brain glucose metabolism in an animal model of depression
