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Novo Nordisk entered 2025 under visible competitive strain, but the company secured a major strategic win in August when subcutaneous Wegovy became the first GLP-1 approved for metabolic dysfunction-associated steatohepatitis (MASH)

Doses of 0.0625 mg or 0.125 mg require extremely precise measurement

Therefore, any relationship between GLP-1 therapy and muscle cramps is more likely to be indirect, mediated through secondary metabolic, nutritional, or fluid balance alterations rather than through direct receptor-mediated effects on muscle tissue

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2 They come with risks that were still learning about