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The search strategy combined Medical Subject Headings (MeSH) and free-text terms, including testosterone replacement therapy, TRT, low testosterone, hypogonadism, GLP-1 receptor agonist, semaglutide, tirzepatide, lean mass, fat-free mass, skeletal muscle, body composition, weight loss, and sarcopenia. Boolean operators (AND/OR) were applied as appropriate

This means that generic semaglutide is exactly as safe and effective to use as any of the brand-name versions that are currently being used in Canada

Obesity treatment - as most other therapeutic areas - will not become winner-takes-all market

The Power of GLP-1 Medications The GLP-1 revolution has transformed how we approach weight loss and metabolic health

This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Subscribe to this journal Receive 12 print issues and online access $259.00 per year only $21.58 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout References Lincoff, A