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To investigate the basis for this difference, we constructed a mouse single cell transcriptomic atlas of body and brain regions most relevant to the action of GLP-1

In two peer-reviewed clinical trials a 12-week study and a 6-month replication study participants taking 400mg of Morosil daily showed measurable improvements in body composition markers compared to placebo, including BMI, and waist and hip circumference

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From study baseline to the end of follow-up, GLP-1RAs treatment resulted in statistically significant decreases in weight (MD=-2.32 kg, 95% CI: -4.21 to -0.43) and BMI (MD=-0.82 kg/m2, 95% CI: -1.47 to -0.17)

The Shift Most Headlines Miss GLPs didnt just improve outcomes

Paired data where patients completed the questionnaire in both years were available in 31.4% (522/1665 [95% CIs 29.2-33.6%])