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Instead, speak to a healthcare professional to: Help manage the side effects Change the prescribed dose Use the medication as part of a comprehensive weight management strategy

Indeed, obesity, often present in people with T2D, is also a major risk factor for CKD development (4), as are associated conditions such as elevated blood pressure and dyslipidemia

With the increasing use of GLP-1 medications for the treatment of type 2 diabetes and obesity, understanding regarding their impact on other medications that require gastric absorption is limited

PLoS One 19 , e0307270 (2024)

102,103 In the context of aging, disruptions in the HPA axis are linked to cognitive decline and mental health issues, including depression

The biggest disadvantage is cost, since sitagliptin is approximately three times more expensive than metformin and about ten times more expensive than the sulfonylureas