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Description
Regardless of their characteristics, it might be reasonable to employ long-acting, sustained release formulations to maintain optimal steady-state therapeutic drug levels in light of difficulties in cognitive and motor function of patients with PD and other neurodegenerative diseases to best achieve compliance and efficacy

Diabetes 59 , 10301037 (2010)

[171] preliminarily showed the excellent efficacy of triple agonists in reversing fatty liver disease in mouse models

Their weight barely changed, but their metabolic health transformed. Defense: And were seeing reports of benefits in people with no weight loss at all
Retatrutide has been studied in a phase 2 trial involving adults without diabetes but with obesity or preobesity (overweight)

Safety and efficacy of an extended-release peptide YY analogue for obesity: a randomized, placebo-controlled, phase 1 trial
