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Over time, obstructive sleep apnea can cause serious cardiac disease and serious neurologic problems, in terms of mental awareness and falling asleep easily during the day, Ren-Fielding said

142 This has important implications for individuals with IBD, as delayed gastric transit may impair the absorption of orally administered therapies such as 5-ASA and thiopurines

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Avraham SA, Hossein J, Somri F, Hawash N, Hochman O

In those cases, lower or more gradual dosing adjustments may be possible because compounded medications are prepared in different concentrations

Seek medical review if these symptoms develop