how long before glp 1 is out of your system Semaglutide GLP-1 First Week Dose: What You Need to Know The GLP-1 Timeline: What to

doi: 10.2147/DMSO.S425642

During meals, GLP-1 is secreted in two stages: a first peak occurs approximately 15 min after the beginning of the meal, when food in the stomach and in the initial portions of the intestine stimulates the release of hormones, such as glucose-dependent insulinotropic polypeptide (GIP), which acts by vagal pathways to stimulate L cells [12]

Matejko B, Kukuka A, Kie-Wilk B, Stpr A, Klupa T, Malecki MT

Kulkarni S, Durham H, Glover L, et al

it activates both GLP-1 and another hormone known as GIP (glucose-dependent insulinotropic polypeptide)

If your expired pen has lost potency, you're essentially getting a lower dose, which could mean: Worsened blood sugar control if you have diabetes Less weight loss than expected A return of the symptoms that the medication was helping manage For people relying on semaglutide for diabetes management, this reduced effectiveness could be particularly dangerous