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The simple truth is that it doesn't

What you should know before using Sejaro Contraindications Do not use Sejaro, if you have: Special warnings and precautions Please consult your physician before using Sejaro

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Many patients hold a lower dose longer if appetite suppression is already effective or if side effects need more time to resolve

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[1] [2] As a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, Mounjaro works by enhancing insulin secretion, suppressing glucagon release, slowing gastric emptying, and reducing appetite