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13 In the CVOTs, GLP-1 RAs were associated with a reduction in new-onset HF among patients with cardiovascular risk factors, but neutral effects were observed on HF events among patients with already diagnosed and stable HF

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Nearly 8% of all prescriptions in March 2026 were for GLP-1 RAs, following the largest quarter-over-quarter percentage point increase in overall GLP-1 RA prescribing observed since the study began in 2019

Cartwright, P

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